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PLAC1 antibody

Anti-PLAC1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85151
Anti-PLAC1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85151
Anti-PLAC1 antibody used in Western Blot (WB). GTX85151

Cat. No. GTX85151

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, ELISA

Reactivity

 Human
Package
100 μg ($399)
See all PLAC1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/mL
ICC/IF 10 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

24 kDa. ( Note )

Positive Control

HeLa Cell Slide(GTX25529) , Human Placenta Tissue Lysate(GTX29186)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

PLAC1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human PLAC1.The immunogen is located within amino acids 130 - 180 of PLAC1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

placenta enriched 1 , CT92 , OOSP2B , OOSP2L

Cellular Localization

Secreted

Background

PLAC1 was initially identified as a protein expressed specifically in the placenta and other cells derived from the trophoblast lineage during embryonic development, but has also been found to be expressed ectopically in a wide range of human malignancies, particularly breast cancers. PLAC1 is a membrane-associated protein that is thought to serve a receptor-like function modulating cell-cell or ligand receptor interactions unique to the maternal-placental interface. Decreased expression of PLAC1 is associated with decreased expression of cyclin D1 and reduced expression of AKT kinase, which, combined with the fact that PLAC1 is expressed on the surface of cancer cells, suggests that PLAC1 may be an effective candidate for immunotherapeutic treatments of cancer.

Database

Research Area

DATA IMAGES

Anti-PLAC1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85151

GTX85151 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX85151 PLAC1 antibody.
Working concentration : 20 μg/ml

Anti-PLAC1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85151

GTX85151 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX85151 PLAC1 antibody.
Working concentration : 10 μg/ml

Anti-PLAC1 antibody used in Western Blot (WB). GTX85151

GTX85151 WB Image

WB analysis of human placenta tissue lysate in (A) the absence and (B) the presence of blocking peptide using GTX85151 PLAC1 antibody.
Working concentration : 1 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399