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PLCG2 antibody

Anti-PLCG2 antibody used in IHC (Paraffin sections) (IHC-P). GTX32793
Anti-PLCG2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32793
Anti-PLCG2 antibody used in Western Blot (WB). GTX32793

Cat No. GTX32793

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P
Reactivity Human, Mouse
Package
100 μl ($329)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:20 - 1:100
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

148 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PLCG2 (NP_002652.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

phospholipase C gamma 2 , APLAID , FCAS3 , PLC-IV , PLC-gamma-2

Background

The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014]

Database

Research Area

DATA IMAGES
Anti-PLCG2 antibody used in IHC (Paraffin sections) (IHC-P). GTX32793

GTX32793 IHC-P Image

IHC-P analysis of mouse heart tissue using GTX32793 PLCG2 antibody.
Dilution : 1:100

Anti-PLCG2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32793

GTX32793 ICC/IF Image

ICC/IF analysis of HeLa cell using GTX32793 PLCG2 antibody.

Anti-PLCG2 antibody used in Western Blot (WB). GTX32793

GTX32793 WB Image

WB analysis of various samples using GTX32793 PLCG2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE
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REVIEW
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Package List Price ($)
$ 329