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PLCG2 antibody

Anti-PLCG2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32793
Anti-PLCG2 antibody used in IHC (Paraffin sections) (IHC-P). GTX32793
Anti-PLCG2 antibody used in Western Blot (WB). GTX32793

Cat. No. GTX32793

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all PLCG2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:20 - 1:100
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

148 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PLCG2 (NP_002652.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

phospholipase C gamma 2 , APLAID , FCAS3 , PLC-IV , PLC-gamma-2

Background

The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014]

Database

Research Area

DATA IMAGES

Anti-PLCG2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32793

GTX32793 ICC/IF Image

ICC/IF analysis of Raw264.7 cells using GTX32793 PLCG2 antibody.
Blue : DAPI
Dilution : 1:100

Anti-PLCG2 antibody used in IHC (Paraffin sections) (IHC-P). GTX32793

GTX32793 IHC-P Image

IHC-P analysis of mouse heart tissue using GTX32793 PLCG2 antibody.
Dilution : 1:100

Anti-PLCG2 antibody used in Western Blot (WB). GTX32793

GTX32793 WB Image

WB analysis of various sample lysates using GTX32793 PLCG2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399