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PLCG2 (phospho Tyr753) antibody

Anti-PLCG2 (phospho Tyr753) antibody used in Western Blot (WB). GTX32240
Anti-PLCG2 (phospho Tyr753) antibody used in IHC (Paraffin sections) (IHC-P). GTX32240

Cat No. GTX32240

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

148 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.42% Potassium phosphate, 0.87% Sodium chloride pH 7.3, 30% glycerol, 0.01% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of PLCG2. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

phospholipase C gamma 2 , APLAID , FCAS3 , PLC-IV , PLC-gamma-2

Background

The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014]

Database

Research Area

DATA IMAGES

Anti-PLCG2 (phospho Tyr753) antibody used in Western Blot (WB). GTX32240

GTX32240 WB Image

WB analysis of TNFa-treated HeLa (A), MCF7 (B), TNFa-treated Raw264.7 (C), mouse kidney (D), rat kidney (E) whole cell lysates using GTX32240 PLCG2 (phospho Tyr753) antibody.

Anti-PLCG2 (phospho Tyr753) antibody used in IHC (Paraffin sections) (IHC-P). GTX32240

GTX32240 IHC-P Image

IHC-P analysis of formalin fixed human breast cancer tissue section using GTX32240 PLCG2 (phospho Tyr753) antibody.
Antigen retrieval : Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0)

REFERENCE

There are currently no references for PLCG2 (phospho Tyr753) antibody (GTX32240). Be the first to share your publications with this product.

REVIEW

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Package List Price ($)
$ 319