GeneTex
United States (US)

PLCL1 antibody

GTX105168_39904_20160809_IHC-P_M_19011506_937.jpg
GTX105168_39904_CT_IHC_19011506_631.jpg

Cat No. GTX105168

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application IHC-P
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

123 kDa. ( Note )

Positive Control

Target recombinant protein

Predict Reactivity

Rat, Bovine, Rhesus Monkey(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.92mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the N-terminus region of human PLCL1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

MGC126580 antibody, MGC138190 antibody, PLCE antibody, PLCL antibody, PLDL1 antibody, PRIP antibody, PLCL1 antibody, "phospholipase C related, but catalytically inactive protein antibody", phospholipase C-deleted in lung carcinoma antibody, phospholipase C-related but catalytically inactive protein antibody, PLC-L1 antibody, "phospholipase C, epsilon antibody", inactive phospholipase C-like protein 1 antibody, phospholipase C-like 1 antibody

Cellular Localization

Cytoplasm

Background

Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity). Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as a inhibitor of PPP1C.

Database

Research Area

DATA IMAGES
GTX105168_39904_20160809_IHC-P_M_19011506_937.jpg

GTX105168 IHC-P Image

PLCL1 antibody detects PLCL1 protein at cytoplasm in mouse brain by immunohistochemical analysis.
Sample: Paraffin-embedded mouse brain.
PLCL1 antibody (GTX105168) diluted at 1:200.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX105168_39904_CT_IHC_19011506_631.jpg

GTX105168 IHC-P Image

PLCL1 antibody detects PLCL1 protein at cytoplasm on human placenta by immunohistochemical analysis.
Sample: Paraffin-embedded placenta.
PLCL1 antibody (GTX105168) dilution: 1:100.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169