Form
Liquid
Buffer
PBS, 5% Trehalose
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Mouse
Immunogen
purified recombinant mouse placenta growth factor 2 expressed in insect Sf 21 cells.
Purification
Purified immunoglobulin
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
placental growth factor , AI854365 , PIGF , Plgf
Cellular Localization
Secreted
Background
Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. PlGF, isolated from a human placental cDNA library, has 53% amino acid sequence homology in the PDGF-region of VEGF. As a result of alternative splicing, three human isoform precursors (PlGF1, PlGF2, and PlGF3) have been described. In mouse tissues, there is only one mRNA encoding the equivalent of human PlGF2.3 Mouse PlGF2 encodes a 158 amino acid precursor protein that shares a 65% homology with human PlGF2. The gene for PlGF is organized into seven exons and is mapped to chromosome 14. Placenta growth factor will potentiate VEGF that is present at low concentrations in vitro and in vivo. PlGF binds with high affinity to Flt1, but not to Flk1/KDR.
Database
Research Area