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PLK1 antibody [MJS1]

Anti-PLK1 antibody [MJS1] used in IHC (Paraffin sections) (IHC-P). GTX01927

Cat. No. GTX01927

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MJS1

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($649)
See all PLK1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100

Note :

IHC-P
The recommended fixative is 10% neutral-buffered formalin for paraffin-embedded tissue sections. Heat Induced Epitope Retreival (HIER) was performed in Epitope Retreival Solution pH6.
Not tested in other applications.

Calculated MW

68 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

107 amino acids from central region of human PLK-1 protein.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

polo like kinase 1 , PLK , STPK13

Cellular Localization

Nucleus

Background

The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy. [provided by RefSeq, Sep 2015]

Database

Research Area

DATA IMAGES

Anti-PLK1 antibody [MJS1] used in IHC (Paraffin sections) (IHC-P). GTX01927

GTX01927 IHC-P Image

IHC-P analysis of squamous cell carcinoma of oropharangeal tissue using GTX01927 PLK1 antibody [MJS1]. Note the intense nuclear and cytoplasmic staining of a proportion of proliferating malignant cells.

REFERENCE

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REVIEW

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Package List Price ($)
$ 649