GeneTex
United States (US)

PMP70 antibody, Internal

GTX88667_2184_WB_18121411_444.jpg
GTX88667_877_IHC-P_18121411_918.jpg

Cat No. GTX88667

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, IHC-F
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.2-0.6μg/ml
IHC-P 2.5-3.8μg/ml
IHC-F Assay dependent

Note :

Human Testis shows vesicular staining in Sertoli cells.
Not tested in other applications.

Calculated MW

75 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88667-PEP).

Specificity/Sensitivity

This antibody is expected to recognize one isoform (NP_002849.1) only.

Predict Reactivity

Mouse, Rat(>80% identity)
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Concentration

0.50mg/ml

Antigen Species

Human

Immunogen

Peptide with sequence C-PDGREDQKRKGISD, from the internal region of the protein sequence according to NP_002849.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

ABCD3 Antibody , ZWS2 Antibody , PXMP1 Antibody , ABC43 Antibody

Background

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
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Database

Research Area

DATA IMAGES
GTX88667_2184_WB_18121411_444.jpg

GTX88667 WB Image

WB analysis of human kidney lysate using GTX88667 PMP70 antibody, Internal.
Dilution : 0.2µg/ml
Loading : 35µg protein in RIPA buffer

GTX88667_877_IHC-P_18121411_918.jpg

GTX88667 IHC-P Image

IHC-P analysis of human testis using GTX88667 PMP70 antibody, Internal.
Antigen retrieval : citrate buffer pH 6
Dilution : 3.8µg/ml