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PMS2 antibody [IHC412]

Anti-PMS2 antibody [IHC412] used in IHC (Paraffin sections) (IHC-P). GTX57194

Cat. No. GTX57194

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 IHC412

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($529)
See all PMS2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Heat-induced epitope retrieval (HIER) at pH 9 for 10 - 30 minutes
Not tested in other applications.

Calculated MW

96 kDa. ( Note )

Positive Control

Colon

PROPERTIES

Form

Liquid

Buffer

Tris buffer, 1% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant Human PMS2 protein.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Pms1 Homolog 2, Mismatch Repair System Component , Hnpcc4 , Mlh4 , Pms2Cl , Pmsl2 , Pms2

Background

This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2008]

Research Area

DATA IMAGES

Anti-PMS2 antibody [IHC412] used in IHC (Paraffin sections) (IHC-P). GTX57194

GTX57194 IHC-P Image

IHC-P analysis of human duodenum tissue using GTX57194 PMS2 antibody [IHC412]

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 529