GeneTex
United States (US)

PMVK antibody [AT21C10]

GTX31956_20151005_ICCIF_18121410_440.jpg

Cat No. GTX31956

Host Mouse
Clonality Monoclonal
Clone Name AT21C10
Isotype IgG2a
Application WB, ICC/IF, FACS, ELISA
Reactivity Human
APPLICATION

Application Note

WB: 1:1000. ICC/IF: 1:100

Calculated MW

22 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human PMVK (1-192aa) purified from E. coli

Purification

By protein-A affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Phosphomevalonate Kinase,Humpmki,Pmk,Pmka,Pmkase,Porok1,Pmvk

Background

This gene encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of this protein is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis. [provided by RefSeq, Sep 2011]

Database

DATA IMAGES
GTX31956_20151005_ICCIF_18121410_440.jpg

GTX31956 ICC/IF Image

ICC/IF analysis of PMVK in PC3 cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human PMVK antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).

Package List Price ($)
$ 319