GeneTex

  • Country / Location Selection

United States (US)

PON1 antibody

Anti-PON1 antibody used in IHC (Paraffin sections) (IHC-P). GTX109561
Anti-PON1 antibody used in Western Blot (WB). GTX109561

Cat. No. GTX109561

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399),
25 μl ($169)
See all PON1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

Positive Control

human plasma , human liver

Predict Reactivity

Rat, Rabbit, Bovine, Pig(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length human PON1 Recombinant protein.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_11170655

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

paraoxonase 1 , ESA , MVCD5 , PON

Cellular Localization

Secreted , extracellular space

Background

The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-PON1 antibody used in IHC (Paraffin sections) (IHC-P). GTX109561

GTX109561 IHC-P Image

PON1 antibody detects PON1 protein at cytoplasm in mouse liver by immunohistochemical analysis.
Sample: Paraffin-embedded mouse liver.
PON1 antibody (GTX109561) diluted at 1:500.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-PON1 antibody used in Western Blot (WB). GTX109561

GTX109561 WB Image

PON1 antibody detects PON1 protein by western blot analysis. Human tissue extracts (30 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with PON1 antibody (GTX109561) diluted at 1:1000.

REFERENCE

Application Reference

Chang CT et al. Journal of Food and Drug Analysis 2018; (Epub) PON-1 carbamylation is enhanced in HDL of uremia patients.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

There are currently no reviews for PON1 antibody (GTX109561). Be the first to share your experience with this product.
Submit a Review
SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169