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PPAR delta antibody [2F9]

Anti-PPAR delta antibody [2F9] used in IHC (Paraffin sections) (IHC-P). GTX34133
Anti-PPAR delta antibody [2F9] used in IHC (Paraffin sections) (IHC-P). GTX34133

Cat No. GTX34133

Host Mouse
Clonality Monoclonal
Clone Name 2F9
Isotype IgG1
Application IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

Specificity/Sensitivity

PPAR Delta Mouse Monoclonal Antibody (2F9) detects endogenous levels of PPAR Delta
PROPERTIES

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant Protein of PPAR Delta

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Peroxisome Proliferator Activated Receptor Delta,Faar,Nr1C2,Nuc1,Nuci,Nucii,Pparb,Ppard

Background

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]

Database

Research Area

DATA IMAGES
Anti-PPAR delta antibody [2F9] used in IHC (Paraffin sections) (IHC-P). GTX34133

GTX34133 IHC-P Image

Immunohistochemistry (IHC) analysis of paraffin-embedded Mouse Brain Tissue using PPAR Delta Mouse Monoclonal Antibody diluted at 1:200.

Anti-PPAR delta antibody [2F9] used in IHC (Paraffin sections) (IHC-P). GTX34133

GTX34133 IHC-P Image

Immunohistochemistry (IHC) analysis of paraffin-embedded Human Brain Tissue using PPAR Delta Mouse Monoclonal Antibody diluted at 1:200.

Package List Price ($)
$ 319