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PPAR gamma (phospho Ser112) antibody

Anti-PPAR gamma (phospho Ser112) antibody used in Western Blot (WB). GTX32242

Cat No. GTX32242

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC

Reactivity

 Human, Mouse, Rat
Package
100 μl ($319)
See all PPAR gamma products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
IHC Assay dependent
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.42% Potassium phosphate, 0.87% Sodium chloride pH 7.3, 30% glycerol, 0.01% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of PPAR gamma. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

peroxisome proliferator activated receptor gamma , CIMT1 , GLM1 , NR1C3 , PPARG1 , PPARG2 , PPARgamma

Cellular Localization

Nucleus,Cytoplasm

Background

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-PPAR gamma (phospho Ser112) antibody used in Western Blot (WB). GTX32242

GTX32242 WB Image

WB analysis of colchicine-treated HeLa (A), colchicine-treated Raw264.7 (B), colchicine-treated PC12 (C), U937 (D) whole cell lysates using GTX32242 PPAR gamma (phospho Ser112) antibody.

REFERENCE

Application Reference

Zhong Y et al. J Neurochem 2019; Crosstalk between Cdk5/p35 and ERK1/2 signalling mediates spinal astrocyte activity via the PPAR帠 pathway in a rat model of chronic constriction injury.
Application : WB, IHC
Reactivity : Rat
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REVIEW

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Package List Price ($)
$ 319