GeneTex
United States (US)

PPM1A antibody [p6c7]

PPM1A-antibody-p6c7-GTX14824-WB-1_18121411_209.jpg

Cat No. GTX14824

Host Mouse
Clonality Monoclonal
Clone Name p6c7
Isotype IgG2b
Application WB, ELISA
Reactivity Human, Mouse
APPLICATION

Application Note

ELISA: Use at an assay dependent dilution. WB: Use at a dilution of 1/250 - 1/1000. Predicted molecular weight: 42 kDa. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

42 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Preservative: 0.1% Sodium Azide; Constituents: PBS. pH 7.4

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full length protein (Human).

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Protein Phosphatase, Mg2+/Mn2+ Dependent 1A,Pp2C-Alpha,Pp2Ca,Pp2Calpha,Ppm1A

Cellular Localization

Cytoplasmic

Background

PPM1A is a Mn2+- or Mg2+-dependent protein serine/threonine phosphatase that inhibits the human stress-responsive p38 and JNK MAPK pathways and regulates cellular stress response in eukaryotes. The PPM (metal-dependent protein phosphatase) family of Ser/Thr protein phosphatases have recently been shown to down-regulate the stress response pathways in eukaryotes. Within the stress pathway, key signaling kinases, which are activated by protein phosphorylation, have been proposed as the in vivo substrates of PP2C, the prototypical member of the PPM family.

Database

Research Area

DATA IMAGES
PPM1A-antibody-p6c7-GTX14824-WB-1_18121411_209.jpg

GTX14824 WB Image

Western blot analysis of mouse liver cytosol extract using GTX14824 at a dilution of 1/250. Proteins were visualised using a goat anti-mouse secondary antibody conjugated to HRP and a DAB detection system.

Package List Price ($)
$ 319