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PPM1B antibody [k1B1]

Anti-PPM1B antibody [k1B1] used in Western Blot (WB). GTX53768

Cat No. GTX53768

Host

Mouse

Clonality

Monoclonal

Clone Name

k1B1

Isotype

IgG2b

Application

WB, ELISA

Reactivity

Human
Package
100 μl ($319)

APPLICATION

Application Note

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000 ~ 3,000. Recommended starting dilution is 1:2,000.

Calculated MW

53 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human PPM1B (1-192aa) purified from E. coli

Purification

By protein-G affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Protein Phosphatase, Mg2+/Mn2+ Dependent 1B , Pp2C-Beta , Pp2C-Beta-X , Pp2Cb , Pp2Cbeta , Ppc2Betax , Ppm1B

Background

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-PPM1B antibody [k1B1] used in Western Blot (WB). GTX53768

GTX53768 WB Image

WB analysis of MCF7 lysate (30ug) using PP2C beta antibody at a dilution of 1:2,000.

REFERENCE

There are currently no references for PPM1B antibody [k1B1] (GTX53768). Be the first to share your publications with this product.

REVIEW

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SDS
Sodium Azide.pdf