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PPM1F antibody, N-term

Anti-PPM1F antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX50878
Anti-PPM1F antibody, N-term used in Western Blot (WB). GTX50878
Anti-PPM1F antibody, N-term used in Western Blot (WB). GTX50878

Cat No. GTX50878

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse
Package
400 μl ($369)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000
IHC-P 1:50-1:100
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.09% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 11-40 amino acids from the N-terminal region of human PPM1F.

Purification

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

protein phosphatase, Mg2+/Mn2+ dependent 1F , CAMKP , CaMKPase , FEM-2 , POPX2 , hFEM-2

Background

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-PPM1F antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX50878

GTX50878 IHC-P Image

IHC-P analysis of human breast carcinoma using GTX50878 PPM1F antibody, N-term.

Anti-PPM1F antibody, N-term used in Western Blot (WB). GTX50878

GTX50878 WB Image

WB analysis of 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PPM1F (Lane 2) using GTX50878 PPM1F antibody, N-term.

Anti-PPM1F antibody, N-term used in Western Blot (WB). GTX50878

GTX50878 WB Image

WB analysis of mouse liver tissue lysate (35ug/lane) using GTX50878 PPM1F antibody, N-term.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf