GeneTex
United States (US)

PPM1L antibody

PPM1L-antibody-GTX87651-WB-1_18121411_957.jpg

Cat No. GTX87651

Host Rabbit
Clonality Polyclonal
Application WB, ELISA
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

41 kDa. ( Note )

Specificity/Sensitivity

PPM1L Antibody detects endogenous levels of total PPM1L protein.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human PPM1L.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Protein phosphatase 2C isoform epsilon, EC 3.1.3.16, PPM1L, Protein phosphatase1like, Protein phosphatase 1like, EC3.1.3.16, Protein phosphatase2C isoform epsilon, Protein phosphatase 1-like, PP2Cepsilon, PP2C-epsilon, PP2C epsilon, Protein phosphatase 1 like

Background

Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6.
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Database

Research Area

DATA IMAGES
PPM1L-antibody-GTX87651-WB-1_18121411_957.jpg

GTX87651 WB Image

Western blot analysis of extracts from Jurkat cells, using PPM1L Antibody. The lane on the right is treated with the synthesized peptide.