APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Dilution |
Assay dependent |
Assay dependent |
Assay dependent |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
0.1M Tris-Glycine (pH7.4), 150mM NaCl, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Purified recombinant human PPP1CA protein fragments expressed in E.coli.
Purification
Affinity purified
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
protein phosphatase 1 catalytic subunit alpha , PP-1A , PP1A , PP1alpha , PPP1A
Cellular Localization
Cytoplasm , Nucleus , nucleoplasm , Nucleolus
Background
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX49238 IHC-P Image
IHC-P analysis of human breast cancer using PPP1A antibody.
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GTX49238 ICC/IF Image
ICC/IF analysis of HeLa cells using PPP1A antibody at a dilution of 1:300.
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GTX49238 WB Image
WB analysis of A431, Jurkat and HeLa lysates using PPP1A antibody at a dilution of 1:1,000.
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REFERENCE
There are currently no references for PPP1A antibody [1C11-C10-H5-E9] (GTX49238). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for PPP1A antibody [1C11-C10-H5-E9] (GTX49238). Be the first to share your experience with this product.