GeneTex
United States (US)

PPP2R4 antibody [N2C3]

GTX105724_WB_19011506_443.jpg
GTX105724_39855_WB_M_brain_19011506_263.jpg

Cat No. GTX105724

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

41 kDa. ( Note )

Positive Control

293T , A431 , mouse brain

Predict Reactivity

Rat, Rabbit(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

6.31mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human PPP2R4. The exact sequence is proprietary.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

MGC2184 antibody, PP2A antibody, PR53 antibody, PTPA antibody, PPP2R4 antibody, PP2A subunit B' isoform PR53 antibody, phosphotyrosyl phosphatase activator antibody, serine/threonine-protein phosphatase 2A activator antibody, PP2A phosphatase activator antibody, serine/threonine-protein phosphatase 2A regulatory subunit B' antibody, "protein phosphatase 2A, regulatory subunit B' (PR 53) antibody", "protein phosphatase 2A activator, regulatory subunit 4 antibody"

Background

Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX105724_WB_19011506_443.jpg

GTX105724 WB Image

Sample(30 μg of whole cell lysate)
A:A431(GTX27909)
10% SDS PAGE
GTX105724 diluted at 1:1000

GTX105724_39855_WB_M_brain_19011506_263.jpg

GTX105724 WB Image

Sample (50 ug of whole cell lysate)
A: Mouse brain
10% SDS PAGE
GTX105724 diluted at 1:1000

SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169