ELISA: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.
GTX10197, 10198, 10199, 10200 and 10201 detect different determinants of proteinase PR3 which have not been fully determined.
Phosphate-buffered saline, pH 7.4, containing 0.1% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
1.6mg/ml(Please refer to the vial label for the specific concentration.)
Human proteinase PR3 purified leukocyte mass
Protein A purified
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ACPA, AGP7, C-ANCA, CANCA, MBN, MBT, NP4, P29, PR-3, PR3, PR 3, C ANCA
Proteinase 3 plays a role in neutrophil response to inflammation. Myeloblastin (PR3) is a polymorphonuclear leukocyte serine protease which degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.