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PRAME antibody [EPR20330]

Anti-PRAME antibody [EPR20330] used in IHC (Paraffin sections) (IHC-P). GTX03315

Cat. No. GTX03315

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 EPR20330

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($1119)
See all PRAME products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:50-1:100

Note :

IHC-P
Pretreatment : EDTA Buffer pH 8.0 for 30 min at RT
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

Positive Control

Melanoma

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment within Human PRAME aa 100 to the C-terminus. The exact sequence is proprietary.

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

preferentially expressed antigen in melanoma , CT130 , MAPE , OIP-4 , OIP4

Cellular Localization

Nucleus , Cell membrane

Background

This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

Database

Research Area

DATA IMAGES

Anti-PRAME antibody [EPR20330] used in IHC (Paraffin sections) (IHC-P). GTX03315

GTX03315 IHC-P Image

IHC-P analysis of human melanoma tissue section using GTX03315 PRAME antibody [EPR20330].

REFERENCE

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REVIEW

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Package List Price ($)
$ 1119