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PRAME antibody

Anti-PRAME antibody used in Western Blot (WB). GTX03709
Anti-PRAME antibody used in Western Blot (WB). GTX03709

Cat. No. GTX03709

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse
Package
100 μl ($359)
See all PRAME products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:2000
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

Predict Reactivity

Dog, Pig(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 150mM NaCl, 50% Glycerol

Preservative

0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human PRAME(Accession P78395), corresponding to amino acid residues W481-C505.

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

preferentially expressed antigen in melanoma , CT130 , MAPE , OIP-4 , OIP4

Cellular Localization

Nucleus , Cell membrane

Background

This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

Database

Research Area

DATA IMAGES

Anti-PRAME antibody used in Western Blot (WB). GTX03709

GTX03709 WB Image

WB analysis of mouse brain tissue lysate using GTX03709 PRAME antibody. The lane on the left was treated with blocking peptide.

Anti-PRAME antibody used in Western Blot (WB). GTX03709

GTX03709 WB Image

WB analysis of HepG2 cell lysates using GTX03709 PRAME antibody. The lane on the left was treated with blocking peptide.

REFERENCE

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REVIEW

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Package List Price ($)
$ 359