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PRDM16 antibody

Anti-PRDM16 antibody used in IHC (Paraffin sections) (IHC-P). GTX03275
Anti-PRDM16 antibody used in IHC (Paraffin sections) (IHC-P). GTX03275
Anti-PRDM16 antibody used in Western Blot (WB). GTX03275
Anti-PRDM16 antibody used in IHC (Paraffin sections) (IHC-P). GTX03275
Anti-PRDM16 antibody used in IHC (Paraffin sections) (IHC-P). GTX03275

Cat. No. GTX03275

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse
Package
100 μg ($419)
See all PRDM16 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/mL
IHC-P 2-20 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

140 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

PRDM16 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human PRDM16 (1120 - 1170).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

PR/SET domain 16 , CMD1LL , KMT8F , LVNC8 , MEL1 , PFM13

Cellular Localization

Nucleus

Background

The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-PRDM16 antibody used in IHC (Paraffin sections) (IHC-P). GTX03275

GTX03275 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX03275 PRDM16 antibody.
Dilution : 2 μg/ml

Anti-PRDM16 antibody used in IHC (Paraffin sections) (IHC-P). GTX03275

GTX03275 IHC-P Image

IHC-P analysis of human brain tissue using GTX03275 PRDM16 antibody.
Dilution : 20 μg/ml

Anti-PRDM16 antibody used in Western Blot (WB). GTX03275

GTX03275 WB Image

WB analysis of K562 cell lysate using GTX03275 PRDM16 antibody.
Dilution : 1 μg/mL.

Anti-PRDM16 antibody used in IHC (Paraffin sections) (IHC-P). GTX03275

GTX03275 IHC-P Image

IHC-P analysis of human brain tissue using GTX03275 PRDM16 antibody.
Dilution : 2 μg/ml

Anti-PRDM16 antibody used in IHC (Paraffin sections) (IHC-P). GTX03275

GTX03275 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX03275 PRDM16 antibody.
Green : Primary antibody
Blue : DAPI
Dilution : 20 μg/ml

REFERENCE

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REVIEW

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Package List Price ($)
$ 419