APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
0.2-2.5 ug/ml |
Not tested in other applications.
Calculated MW
Positive Control
293T , human fetal liver , human fetal muscle , human placenta
PROPERTIES
Form
Liquid
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide corresponding to a N-terminal region of Human PRMT7
Purification
Affinity Purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
protein arginine methyltransferase 7 , SBIDDS
Cellular Localization
Cytoplasm, cytosol,Nucleus
Background
This gene encodes a member of the protein arginine N-methyltransferase family of proteins. The encoded enzyme transfers single methyl groups to arginine residues to generate monomethylarginines on histone proteins as well as other protein substrates. This enzyme plays a role in a wide range of biological processes, including neuronal differentiation, male germ line imprinting, small nuclear ribonucleoprotein biogenesis, and regulation of the Wnt signaling pathway. Mutations in this gene underlie multiple related syndromes in human patients characterized by intellectual disability, short stature and other features. The encoded protein may promote breast cancer cell invasion and metastasis in human patients. [provided by RefSeq, May 2017]
Database
Research Area
DATA IMAGES
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GTX47432 WB Image
WB analysis of 293T cells using GTX47432 PRMT7 antibody at 1μg/ml.
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GTX47432 WB Image
WB analysis of human fetal liver tissue using GTX47432 PRMT7 antibody at 0.2-1μg/ml.
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GTX47432 WB Image
WB analysis of human fetal muscle tissue using GTX47432 PRMT7 antibody at 1μg/ml.
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GTX47432 WB Image
WB analysis of human placenta tissue using GTX47432 PRMT7 antibody at 1μg/ml.
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REFERENCE
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REVIEW
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