GeneTex

  • Country / Location Selection

United States (US)

PRTFDC1 antibody

Anti-PRTFDC1 antibody used in Western Blot (WB). GTX85380

Cat. No. GTX85380

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ELISA

Reactivity

 Human, Rat
Package
100 μg ($399)
See all PRTFDC1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

26 kDa. ( Note )

Positive Control

Human Brain Tissue Lysate(GTX27918)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

PRTFDC1 antibody was raised against a 14 amino acid synthetic peptide from near the center of human PRTFDC1.The immunogen is located within amino acids 90 - 140 of PRTFDC1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

phosphoribosyl transferase domain containing 1 , HHGP

Background

Phosphoribosyl transferase domain containing 1 (PRTFDC1) is highly homologous to the hypoxanthine phosphoribosyltransferase (HPRT1) and may have arisen from a gene duplication event of a common ancestor gene. Recently, it was shown that CpG islands in the PRTFDC1 promoter could be hypermethylated in ovarian cancers and oral squamous-cell carcinomas (OSCC), leading to gene silencing. Restoration of PRTFDC1 expression in OSCC inhibited cell growth in colony-formation assays, while knockdown of PRTFDC1 expression in OSCC that expressed the gene promoted cell growth. These results suggest that PRTFDC1 can act as a tumor-suppressor gene. At least three isoforms of PRTFDC1 are known to exist.

Database

Research Area

DATA IMAGES

Anti-PRTFDC1 antibody used in Western Blot (WB). GTX85380

GTX85380 WB Image

WB analysis of human brain tissue lysate in the (A) absence and (B) presence of blocking peptide using GTX85380 PRTFDC1 antibody.
Working concentration : 1 μg/ml

REFERENCE

There are currently no references for PRTFDC1 antibody (GTX85380). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for PRTFDC1 antibody (GTX85380). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399