GeneTex
United States (US)

PRX II antibody

GTX15572_267_ICC-IF_19011519_354.jpg

Cat No. GTX15572

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:10,000
ICC/IF 1:500
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

22 kDa. ( Note )

Specificity/Sensitivity

This antibody is specific for Prx 2 and shows no cross-reactivity with other Prx isoforms.
PROPERTIES

Form

Liquid

Buffer

Serum, 0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthetic peptide corresponding to residues L(104) L A D V T R R L S E D(115) of human Peroxiredoxin 2.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Peroxiredoxin 2,Hel-S-2A,Nkef-B,Nkefb,Prp,Prx2,Prxii,Ptx1,Tdpx1,Tpx1,Tsa,Prdx2

Cellular Localization

Cytoplasm

Background

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013]

Database

Research Area

DATA IMAGES
GTX15572_267_ICC-IF_19011519_354.jpg

GTX15572 ICC/IF Image

ICC/IF analysis of TSU-Pr1 cells using GTX15572 PRX II antibody.

Package List Price ($)
$ 319