APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:10,000 |
1:500 |
Assay dependent |
Not tested in other applications.
Calculated MW
Product Note
This antibody is specific for Prx 2 and shows no cross-reactivity with other Prx isoforms.
PROPERTIES
Form
Liquid
Buffer
Serum
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species
Human
Immunogen
Synthetic peptide corresponding to residues L(104) L A D V T R R L S E D(115) of human Peroxiredoxin 2.
Purification
Unpurified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
peroxiredoxin 2 , HEL-S-2a , NKEF-B , NKEFB , PRP , PRX2 , PRXII , PTX1 , TDPX1 , TPX1 , TSA
Cellular Localization
Cytoplasm
Background
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013]
Database
Research Area
DATA IMAGES
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GTX15572 ICC/IF Image
ICC/IF analysis of TSU-Pr1 cells using GTX15572 PRX II antibody.
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REFERENCE
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REVIEW
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