APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Dilution |
| 1:1,000 |
Not tested in other applications.
Calculated MW
Specificity/Sensitivity
No cross reactivity with Human Albumin, AFP, CEA, PAP, CA-125, CA19-9 or CA 15-3.
PROPERTIES
Form
Liquid
Buffer
0.05 M Potassium Phosphate, 0.085% sodium chloride, pH 7.2, mg/ml BSA, Proclin
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration
0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Human PSA
Purification
Purified by S-300 Column Chromatography
Conjugation
Horseradish peroxidase(HRP)
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
Kallikrein Related Peptidase 3,Aps,Klk2A1,Psa,Hk3,Klk3
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Database
