Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Dilution |
| Assay dependent |
| Assay dependent |
|
Note :
Capture: GTX39427/GTX39425/GTX39429/GTX39426, Detection: GTX39428 or Capture: GTX39428, Detection: GTX39427/GTX39425/GTX39429.
|
Not tested in other applications.
Calculated MW
Specificity/Sensitivity
In sandwich ELISA, reacts with total PSA (free PSA and PSA complexed with ACT).
Form
Liquid
Buffer
PBS pH 7.4 + 0.2, 0.05% sodium azide
Concentration
6.86mg/ml
Antigen Species
Human
Immunogen
Purified PSA
Purification
Protein A purified
Conjugation
Unconjugated
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Synonyms
HK3 Antibody , KLK3 Antibody , PSA Antibody , APS Antibody , KLK2A1 Antibody
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Database
