GeneTex
United States (US)

PSA (Total) antibody [B732M]

Cat No. GTX39425

Host Mouse
Clonality Monoclonal
Clone Name B732M
Isotype IgG2b
Application ELISA, sELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ELISA Assay dependent
sELISA Assay dependent

Note :

Capture: GTX39427/GTX39425/GTX39429/GTX39426, Detection: GTX39428 or Capture: GTX39428, Detection: GTX39427/GTX39425/GTX39429.
Not tested in other applications.

Calculated MW

29 kDa. ( Note )

Specificity/Sensitivity

In sandwich ELISA, reacts with total PSA (free PSA and PSA complexed with ACT).
PROPERTIES

Form

Liquid

Buffer

PBS pH 7.4 + 0.2, 0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

4.54mg/ml

Antigen Species

Human

Immunogen

Purified PSA

Purification

Protein A purified

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

APS Antibody , KLK2A1 Antibody , PSA Antibody , KLK3 Antibody , HK3 Antibody

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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Database

Package List Price ($)
$ 289