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PSA antibody [PS1]

Cat No. GTX10188

Host Mouse
Clonality Monoclonal
Clone Name PS1
Isotype IgG1
Application ELISA, sELISA
Reactivity Human
Package
100 μg ($219)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ELISA Assay dependent
sELISA Assay dependent

Note :

sELISA
Capture : GTX10188/GTX10189, Detection : GTX10189/GTX10188

Not tested in other applications.

Calculated MW

28.74 kDa. ( Note )

Specificity/Sensitivity

This antibody reacts with free PSA (epitope 1) . It does not cross react with kallikrein 2.
PROPERTIES

Form

Liquid

Buffer

10 mM Tris pH 7.5, 0.15 M NaCl, 0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4º C.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human PSA antigen purified from seminal plasma.

Purification

Purified by ion exchange chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Kallikrein Related Peptidase 3 , Aps , Klk2A1 , Psa , Hk3 , Klk3

Cellular Localization

Secreted

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE
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REVIEW
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Package List Price ($)
$ 219