*Optimal dilutions/concentrations should be determined by the researcher.
Capture : GTX10188/GTX10189, Detection : GTX10189/GTX10188
Not tested in other applications.
This antibody reacts with total PSA (epitope 3). It cross reacts with kallikrein 2.
10 mM Tris pH 7.5, 0.15 M NaCl, 0.05% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4º C.
Human PSA antigen purified from seminal plasma.
Purified by ion exchange chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Kallikrein Related Peptidase 3 , Aps , Klk2A1 , Psa , Hk3 , Klk3
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]