GeneTex
United States (US)

PSA antibody

GTX29537_IHC-P_18121410_888.jpg
PSA-antibody_IHC (Formalin-fixed paraffin-embedded sections)_GTX29537-1_18121411_167.jpg

Cat No. GTX29537

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application IHC-P, IHC-Fr
Reactivity Human
APPLICATION

Application Note

This antibody may be diluted to a titer of 1:50-1:150 in an ABC method. We suggest an incubation period of 30-60 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation and dilutions should be determined by the user.

Calculated MW

29 kDa. ( Note )

Specificity/Sensitivity

This antibody reacts with PSA. Staining was observed in the prostatic ductal epithelium of normal and neoplastic prostate.No staining with any other cell type has been observed.
PROPERTIES

Form

Liquid

Buffer

This antibody contains sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

1.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Prostate specific antigen isolated from human seminal plasma.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Kallikrein Related Peptidase 3,Aps,Klk2A1,Psa,Hk3,Klk3

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates two transcript variants encoding different isoforms. Additional transcript variants have been described, but it is unclear if these transcripts are normally expressed or if they are specific to benign or malignant tumors.

Database

DATA IMAGES
GTX29537_IHC-P_18121410_888.jpg

GTX29537 IHC-P Image

IHC-P analysis of prostate carcinoma using PSA antibody.

PSA-antibody_IHC (Formalin-fixed paraffin-embedded sections)_GTX29537-1_18121411_167.jpg

GTX29537 IHC-P Image

Formalin fixed paraffin embedded human prostate stained with PSA antibody (cat. # GTX29537).

Package List Price ($)
$ 289