*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
rat brain , mouse brain
Human, Bovine(>80% identity)
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of mouse PSD95. The exact sequence is proprietary.
Affinity purified by Protein A.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
discs large MAGUK scaffold protein 4,Dlgh4,PSD-95,PSD95,SAP90,SAP90A
Membrane , Cell junction , synapse , postsynaptic cell membrane , postsynaptic density , synapse
Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ACCN3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.
GTX634291 WB Image
Mouse tissue extract (50 µg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with PSD95 antibody [GT1234] (GTX634291) diluted at 1:5000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.
GTX634291 ICC/IF Image
PSD95 antibody [GT1234] detects PSD95 protein by immunofluorescent analysis.Sample: DIV9 rat E18 primary cortical neuron cells were fixed in 4% paraformaldehyde at RT for 15 min.Green: PSD95 stained by PSD95 antibody [GT1234] (GTX634291) diluted at 1:500.Red: NeuN, stained by NeuN antibody (GTX132974) diluted at 1:500.Blue: Fluoroshield with DAPI (GTX30920).
GTX634291 WB Image
Rat tissue extract (50 µg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with PSD95 antibody [GT1234] (GTX634291) diluted at 1:5000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.