GeneTex
United States (US)

PSD95 antibody, Internal (near C-Terminus)

GTX88388_2325_WB_18122102_594.jpg

Cat No. GTX88388

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.3-1μg/ml
Not tested in other applications.

Calculated MW

80 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88388-PEP).

Specificity/Sensitivity

This antibody is expected to recognize both reported isoforms (NP_001356.1; NP_001122299.1)

Predict Reactivity

Human, Mouse, Bovine, Dog(>80% identity)
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-EEQARKAFDRATK, from the internal region (near C-Terminus) of the protein sequence according to NP_001356.1; NP_001122299.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Discs Large Maguk Scaffold Protein 4,Psd95,Sap-90,Sap90,Dlg4

Cellular Localization

High levels in postsynaptic density of neurons in the forebrain. Also in presynaptic region of inhibitory synapses formed by cerebellar basket cells on axon hillocks of Purkinje cells.

Background

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX88388_2325_WB_18122102_594.jpg

GTX88388 WB Image

WB analysis of rat brain lysate using GTX88388 PSD95 antibody, Internal (near C-Terminus).
Dilution : 0.3µg/ml
Loading : 35µg protein in RIPA buffer

Package List Price ($)
$ 329