*Optimal dilutions/concentrations should be determined by the researcher.
Human Tonsil shows efined staining in a subset of cells.
Not tested in other applications.
The peptide used to generate this antibody is available for purchase (GTX88408-PEP).
Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.
Peptide with sequence C-PTEPVKRSGRYH, from the internal region of the protein sequence according to NP_002792.1.
Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
BETA2I Antibody , LMP10 Antibody , MECL1 Antibody
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. [provided by RefSeq, Jul 2008]
GTX88408 IHC-P Image
IHC-P analysis of human tonsil using GTX88408 PSMB10 antibody, Internal.
Antigen retrieval : citrate buffer pH 6
Dilution : 5µg/ml
GTX88408 WB Image
WB analysis of human lung lysate using GTX88408 PSMB10 antibody, Internal.
Dilution : 0.3µg/ml
Loading : 35µg protein in RIPA buffer