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PSMC2 antibody

Anti-PSMC2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54583
Anti-PSMC2 antibody used in Western Blot (WB). GTX54583
Anti-PSMC2 antibody used in IHC (Paraffin sections) (IHC-P). GTX54583
Anti-PSMC2 antibody used in IHC (Paraffin sections) (IHC-P). GTX54583

Cat No. GTX54583

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IHC-P

Reactivity

Human, Mouse
Package
100 μl ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

49 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human PSMC2 (NP_002794.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

proteasome 26S subunit, ATPase 2 , MSS1 , Nbla10058 , S7

Cellular Localization

Cytoplasm

Background

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with several of the basal transcription factors so, in addition to participation in proteasome functions, this subunit may participate in the regulation of transcription. This subunit may also compete with PSMC3 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2011]

Database

Research Area

DATA IMAGES

Anti-PSMC2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54583

GTX54583 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX54583 PSMC2 antibody.
Blue : DAPI

Anti-PSMC2 antibody used in Western Blot (WB). GTX54583

GTX54583 WB Image

WB analysis of various sample lysates using GTX54583 PSMC2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-PSMC2 antibody used in IHC (Paraffin sections) (IHC-P). GTX54583

GTX54583 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX54583 PSMC2 antibody.
Dilution : 1:100

Anti-PSMC2 antibody used in IHC (Paraffin sections) (IHC-P). GTX54583

GTX54583 IHC-P Image

IHC-P analysis of mouse heart tissue using GTX54583 PSMC2 antibody.
Dilution : 1:100

REFERENCE

There are currently no references for PSMC2 antibody (GTX54583). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for PSMC2 antibody (GTX54583). Be the first to share your experience with this product.
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339