GeneTex

  • Country / Location Selection

United States (US)

PSMC3 antibody

Anti-PSMC3 antibody used in Western Blot (WB). GTX55764
Anti-PSMC3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55764
Anti-PSMC3 antibody used in IHC (Paraffin sections) (IHC-P). GTX55764
Anti-PSMC3 antibody used in IHC (Paraffin sections) (IHC-P). GTX55764
Anti-PSMC3 antibody used in IHC (Paraffin sections) (IHC-P). GTX55764

Cat. No. GTX55764

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all PSMC3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

49 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human PSMC3 (NP_002799.3).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

proteasome 26S subunit, ATPase 3 , TBP1

Cellular Localization

Cytoplasm,Nucleus

Background

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-PSMC3 antibody used in Western Blot (WB). GTX55764

GTX55764 WB Image

WB analysis of various sample lysates using GTX55764 PSMC3 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-PSMC3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55764

GTX55764 ICC/IF Image

ICC/IF analysis of MCF7 cells using GTX55764 PSMC3 antibody.

Anti-PSMC3 antibody used in IHC (Paraffin sections) (IHC-P). GTX55764

GTX55764 IHC-P Image

IHC-P analysis of rat kidney tissue using GTX55764 PSMC3 antibody.
Dilution : 1:100

Anti-PSMC3 antibody used in IHC (Paraffin sections) (IHC-P). GTX55764

GTX55764 IHC-P Image

IHC-P analysis of rat liver tissue using GTX55764 PSMC3 antibody.
Dilution : 1:100

Anti-PSMC3 antibody used in IHC (Paraffin sections) (IHC-P). GTX55764

GTX55764 IHC-P Image

IHC-P analysis of rat intestine tissue using GTX55764 PSMC3 antibody.
Dilution : 1:200

REFERENCE

There are currently no references for PSMC3 antibody (GTX55764). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for PSMC3 antibody (GTX55764). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399