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PSMC5 antibody

Anti-PSMC5 antibody used in Western Blot (WB). GTX32819
Anti-PSMC5 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32819

Cat No. GTX32819

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human, Mouse, Rat
Package
100 μl ($329)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

46 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 127-406 of human PSMC5 (NP_002796.4).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

proteasome 26S subunit, ATPase 5 , S8 , SUG-1 , SUG1 , TBP10 , TRIP1 , p45 , p45/SUG

Cellular Localization

Cytoplasm,Nucleus

Background

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

Database

Research Area

DATA IMAGES
Anti-PSMC5 antibody used in Western Blot (WB). GTX32819

GTX32819 WB Image

WB analysis of various samples using GTX32819 PSMC5 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-PSMC5 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32819

GTX32819 ICC/IF Image

ICC/IF analysis of MCF-7 cell using GTX32819 PSMC5 antibody.
Blue : DAPI

REFERENCE
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REVIEW
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Package List Price ($)
$ 329