APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:500-1:1000 |
1:50-1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic peptide, corresponding to amino acids 281-330 of Human PSMD11.
Purification
Purified by antigen-affinity chromatography
From serum
Purity
> 95% (by SDS-PAGE)
Conjugation
Unconjugated
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
proteasome 26S subunit, non-ATPase 11 , Rpn6 , S9 , p44.5
Cellular Localization
Nucleus,Cytoplasm, cytosol
Background
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
Database
Research Area
DATA IMAGES
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GTX66726 IHC-P Image
IHC-P analysis of human breast carcinoma tissue using GTX66726 PSMD11 antibody. Dilution : 1:100
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GTX66726 WB Image
WB analysis of various samples using GTX66726 PSMD11 antibody. Lane1 : HCC827 whole cell lysate(40ug) Lane2 : HCT116 whole cell lysate(40ug) Lane3 : 786-O whole cell lysate(40ug) Lane4 : The Muscle tissue lysate of Mouse(40ug) Lane5 : PC12 whole cell lysate(40ug) Dilution : 1:500
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GTX66726 WB Image
WB analysis of various samples using GTX66726 PSMD11 antibody. Lane1 : HEK293T whole cell lysate(40ug)
Lane2 : PANC1 whole cell lysate(40ug)
Lane3 : L02 whole cell lysate(40ug)
Lane4 : H9C2 whole cell lysate(40ug)
Lane5 : CT26 whole cell lysate(40ug) Dilution : 1:500
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GTX66726 WB Image
WB analysis of various samples using GTX66726 PSMD11 antibody. Lane1 : A549 whole cell lysate(40ug) Lane2 : K562 whole cell lysate(40ug) Lane3 : The Heart tissue lysate of Rat(40ug) Lane4 : The Heart tissue lysate of Mouse(40ug) Dilution : 1:500
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REFERENCE
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REVIEW
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