*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
A549 , HeLa , HepG2 , HCT116
Mouse, Rat, Zebrafish, Bovine, Xenopus laevis, Rhesus Monkey(>80% identity)
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Recombinant protein encompassing a sequence within the center region of human PSMD7. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
MOV34 antibody, P40 antibody, Rpn8 antibody, S12 antibody, PSMD7 antibody, 26S proteasome regulatory subunit S12 antibody, proteasome subunit p40 antibody, Mov34 homolog antibody, Moloney leukemia virus-34 proviral integration antibody, 26S proteasome non-ATPase regulatory subunit 7 antibody, "proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog) antibody", 26S proteasome regulatory subunit rpn8 antibody, "proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 antibody"
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17. [provided by RefSeq]
GTX103677 WB Image
Sample (30 ug of whole cell lysate)
10% SDS PAGE
GTX103677 diluted at 1:500
GTX103677 ICC/IF Image
Immunofluorescence analysis of methanol-fixed HeLa, using PSMD7(GTX103677) antibody at 1:500 dilution.