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PTCH2 antibody

Anti-PTCH2 antibody used in Western Blot (WB). GTX70350

Cat No. GTX70350

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ELISA

Reactivity

Human
Package
100 μg ($289)

APPLICATION

Application Note

Western blot - Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.

Specificity/Sensitivity

Reacts with residues 226-235 [GPFASLEGFR] of the human PTCH2 protein. Cross reacts with mouse.

PROPERTIES

Form

Liquid

Buffer

PBS containing 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Purification

Affinity purified IgG

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Background

Mutations of the human Patched tumor suppressor gene (PTCH) have been identified in individuals with the nevoid basal cell carcinoma syndrome (NBCCS) as well as in sporadic basal cell carcinomas and medulloblastomas. PTCH2 has a frameshift mutation resulting in a truncated PTCH2 protein.

Research Area

DATA IMAGES

Anti-PTCH2 antibody used in Western Blot (WB). GTX70350

GTX70350 WB Image

Western blot analysis of human PTCH2 in fetal brain lysate.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf