GeneTex
  • Country / Location Selection

United States (US)

PTEN antibody [9E8]

Anti-PTEN antibody [9E8] used in IHC (Paraffin sections) (IHC-P). GTX34151

Cat No. GTX34151

Host

Mouse

Clonality

Monoclonal

Clone Name

9E8

Isotype

IgG1

Application

IHC-P

Reactivity

Human
Package
100 μl ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

47 kDa. ( Note )

Specificity/Sensitivity

PTEN Mouse Monoclonal Antibody (9E8) detects endogenous levels of PTEN

PROPERTIES

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthetic Peptide of PTEN

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Phosphatase And Tensin Homolog , 10Q23Del , Bzs , Cws1 , Dec , Glm2 , Mham , Mmac1 , Pten1 , Ptenbeta , Tep1 , Pten

Background

This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-PTEN antibody [9E8] used in IHC (Paraffin sections) (IHC-P). GTX34151

GTX34151 IHC-P Image

Immunohistochemistry (IHC) analysis of paraffin-embedded Human Lung Carcinoma Tissue using PTEN Mouse Monoclonal Antibody diluted at 1:200.

REFERENCE

There are currently no references for PTEN antibody [9E8] (GTX34151). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for PTEN antibody [9E8] (GTX34151). Be the first to share your experience with this product.
Package List Price ($)
$ 319