APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
10 μg/ml |
Note :
IHC-P
Heat induced antigen retrieval in pH 6.0 citrate buffer
|
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse, Elephant, Gibbon, Gorilla, Marmoset, Opossum, Panda, Pufferfish, Turkey, Xenopus, Platypus, Stickleback, Pike(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 14 amino acid peptide near N-terminus of human PTGES.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
prostaglandin E synthase , MGST1L1 , MGSTIV , MPGES , PGES , PIG12 , PP102 , PP1294 , PTGES , TP53I12 , mPGES1 , Prostaglandin E synthase , PGE synthase
Cellular Localization
Membrane
Background
The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX85793 IHC-P Image
IHC-P analysis of human testis tissue using GTX85793 PTGES antibody. Antigen retrieval : Heat-induced antigen retrieval
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REFERENCE
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REVIEW
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