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PTP4A3 antibody [N1C3]

Anti-PTP4A3 antibody [N1C3] used in Western Blot (WB). GTX100600

Cat. No. GTX100600

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, WB-Ag

Reactivity

 Zebrafish
Package
100 μl ($399),
25 μl ($169)
See all PTP4A3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
WB-Ag Assay dependent
Not tested in other applications.

Calculated MW

20 kDa. ( Note )

Predict Reactivity

Human, Mouse, Rat, Bovine, Xenopus tropicalis, Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human PTP4A3. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2037800

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

protein tyrosine phosphatase 4A3 , PRL-3 , PRL-R , PRL3

Cellular Localization

Cell membrane , Early endosome

Background

The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-PTP4A3 antibody [N1C3] used in Western Blot (WB). GTX100600

GTX100600 WB Image

Sample (30 μg of whole cell lysate)
A: zebrafish eye
12% SDS PAGE
GTX100600 diluted at 1:1000

REFERENCE

Application Reference

Smith CN et al. PLoS One 2023; 18 (5) : e0285964 Development and characterization of nanobodies that specifically target the oncogenic Phosphatase of Regenerating Liver-3 (PRL-3) and impact its interaction with a known binding partner, CNNM3.
Li CJ et al. J Hepatocell Carcinoma 2023; 10 : 123-138
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SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169