APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
2 - 3 μg/ml |
Not tested in other applications.
Predict Reactivity
Mouse, Rat, Bovine, Dog, Hamster, Monkey, Bat, Gibbon, Horse, Marmoset, Panda(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 20 amino acid peptide from cytoplasmic domain of human PTPRE.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_375445
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
protein tyrosine phosphatase receptor type E , HPTPE , PTPE , PTPRE , RPTPEPSILON , protein tyrosine phosphatase, receptor type E , PTP epsilon
Cellular Localization
Cell membrane,Cytoplasm
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels. [provided by RefSeq, Oct 2015]
Database
Research Area
DATA IMAGES
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GTX70949 IHC-P Image
IHC-P analysis of human colon, submucosal vessel tissue using GTX70949 PTPRE antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX70949 IHC-P Image
IHC-P analysis of human brain, glioblastoma tissue using GTX70949 PTPRE antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX70949 IHC-P Image
IHC-P analysis of human prostate, carcinoma tissue using GTX70949 PTPRE antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX70949 IHC-P Image
IHC-P analysis of human nerves in prostate carcinoma tissue using GTX70949 PTPRE antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX70949 IHC-P Image
IHC-P analysis of human skin, melanoma tissue using GTX70949 PTPRE antibody. Antigen retrieval : Heat-induced antigen retrieval
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REFERENCE
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REVIEW
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