*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
The peptide used to generate this antibody is available for purchase (GTX88474-PEP).
This antibody is expected to recognize all reported isoforms (NP_071285.1; NP_148934.1; NP_003880.3).
Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.
Peptide with sequence EQFAITLKSYIECNR, from the internal region of the protein sequence according to NP_003880.3; NP_071285.1; NP_148934.1.
Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ONR1 Antibody , PAR2 Antibody , NR1I2 Antibody , PAR1 Antibody , SAR Antibody , PAR Antibody , PRR Antibody , SXR Antibody , BXR Antibody , PARQ Antibody
This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. [provided by RefSeq, Jul 2008]