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Pannexin 1 antibody

Anti-Pannexin 1 antibody used in Western Blot (WB). GTX04619
Anti-Pannexin 1 antibody used in IHC (Free Floating) (IHC (Free Floating)). GTX04619

Cat. No. GTX04619

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC (Free Floating)

Reactivity

 Human, Mouse, Rat
Package
50 μl ($669)
See all Pannexin 1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC (Free Floating) Assay dependent
Not tested in other applications.

Calculated MW

48 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.8 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide (C)KEPTEPKFKGLRLE, corresponding to amino acid residues 18- 31 of human PANX1 (Accession Q96RD7).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

pannexin 1 , MRS1 , PX1 , UNQ2529

Cellular Localization

Cell membrane , Cell junction, gap junction , Endoplasmic reticulum membrane

Background

The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Pannexin 1 antibody used in Western Blot (WB). GTX04619

GTX04619 WB Image

WB analysis of various samples using GTX04619 Pannexin 1 antibody prior incubated with (Lane 5-8) or without (Lane 1-4) blocking peptide.
Lane 1 and 5 : Mouse heart tissue lysate
Lane 2 and 6 : Rat heart tissue lysate
Lane 3 and 7 : Mouse brain tissue lysate
Lane 4 and 8 : Rat brain tissue lysate
Dilution : 1:400

Anti-Pannexin 1 antibody used in IHC (Free Floating) (IHC (Free Floating)). GTX04619

GTX04619 IHC (Free Floating) Image

IHC (Free floating) analysis of rat brain tissue using GTX04619 Pannexin 1 antibody. PANX1 staining is apparent in cells with neuronal outline (vertical arrows) and apical dendrites (horizontal arrows) in the parietal cingulated cortex region.
Green : Primary antibody
Blue : DAPI

REFERENCE

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REVIEW

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Package List Price ($)
$ 669