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Pannexin 1 antibody

Anti-Pannexin 1 antibody used in Western Blot (WB). GTX31510
Anti-Pannexin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX31510

Cat. No. GTX31510

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all Pannexin 1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
IHC-P 20 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

48 kDa. ( Note )

Positive Control

Human Ovary Tissue Lysate(GTX29180) , Human Ovary Tissue Slide

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Rabbit polyclonal PANX1 antibody was raised against a 17 amino acid peptide near the amino terminus of human PANX1.The immunogen is located within amino acids 70 - 120 of PANX1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887617

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

pannexin 1 , MRS1 , PX1 , UNQ2529

Cellular Localization

Cell membrane,Endoplasmic reticulum membrane

Background

The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Pannexin 1 antibody used in Western Blot (WB). GTX31510

GTX31510 WB Image

WB analysis of human ovary tissue lysate using GTX31510 Pannexin 1 antibody.
Working concentration : 1 μg/ml

Anti-Pannexin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX31510

GTX31510 IHC-P Image

IHC-P analysis of human ovary tissue using GTX31510 Pannexin 1 antibody.
Working concentration : 20 μg/ml

REFERENCE

Application Reference

Zhang Z et al. Inflammation 2019; (Epub) Probenecid Relieves Cerebral Dysfunction of Sepsis by Inhibiting Pannexin 1-Dependent ATP Release.
Application : WB
Reactivity : Mouse
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399