APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1 - 2 μg/mL |
| 5 μg/mL |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Human Brain Tissue Slide(GTX22203) , Human Cerebellum Tissue Lysate(GTX29124)
Product Note
PARK2 antibody is human specific.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Parkin antibody was raised against a 17 amino acid peptide near the amino terminus of human Parkin.The immunogen is located within amino acids 110 - 160 of Parkin.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
parkin RBR E3 ubiquitin protein ligase , AR-JP , LPRS2 , PARK2 , PDJ
Cellular Localization
Cytoplasm, cytosol,Nucleus,Endoplasmic reticulum,Mitochondrion
Background
The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX31927 IHC-P Image
IHC-P analysis of human brain tissue using GTX31927 Parkin antibody.
Working concentration : 20 μg/ml
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GTX31927 IHC-P Image
IHC-P analysis of human brain tissue using GTX31927 Parkin antibody.
Working concentration : 5 μg/ml
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GTX31927 WB Image
WB analysis of human cerebellum tissue lysate using GTX31927 Parkin antibody.
Working concentration : 1 μg/ml
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REFERENCE
There are currently no references for Parkin antibody (GTX31927). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Parkin antibody (GTX31927). Be the first to share your experience with this product.
