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Parkin antibody

Anti-Parkin antibody used in IHC (Paraffin sections) (IHC-P). GTX31927
Anti-Parkin antibody used in IHC (Paraffin sections) (IHC-P). GTX31927
Anti-Parkin antibody used in Western Blot (WB). GTX31927

Cat No. GTX31927

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, ELISA

Reactivity

Human
Package
100 μg ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

52 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , Human Cerebellum Tissue Lysate(GTX29124)

Product Note

PARK2 antibody is human specific.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Parkin antibody was raised against a 17 amino acid peptide near the amino terminus of human Parkin.The immunogen is located within amino acids 110 - 160 of Parkin.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

parkin RBR E3 ubiquitin protein ligase , AR-JP , LPRS2 , PARK2 , PDJ

Cellular Localization

Cytoplasm, cytosol,Nucleus,Endoplasmic reticulum,Mitochondrion

Background

The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Parkin antibody used in IHC (Paraffin sections) (IHC-P). GTX31927

GTX31927 IHC-P Image

IHC-P analysis of human brain tissue using GTX31927 Parkin antibody.
Working concentration : 20 μg/ml

Anti-Parkin antibody used in IHC (Paraffin sections) (IHC-P). GTX31927

GTX31927 IHC-P Image

IHC-P analysis of human brain tissue using GTX31927 Parkin antibody.
Working concentration : 5 μg/ml

Anti-Parkin antibody used in Western Blot (WB). GTX31927

GTX31927 WB Image

WB analysis of human cerebellum tissue lysate using GTX31927 Parkin antibody.
Working concentration : 1 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399