Parkin peptide is used for blocking the activity of Parkin antibody (catalog number GTX31927). It usually blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37ºC.
*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
PBS pH7.2 (10mM NaH₂PO₄, 10mM Na₂HPO₄, 130mM NaCl), 0.1% BSA
0.02% Sodium azide
Store as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
200 μg/ml (Please refer to the vial label for the specific concentration.)
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Parkin Rbr E3 Ubiquitin Protein Ligase , Ar-Jp , Lprs2 , Park2 , Pdj , Prkn
The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008]