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Parkin (phospho Ser101) antibody

Anti-Parkin (phospho Ser101) antibody used in Western Blot (WB). GTX31094
Anti-Parkin (phospho Ser101) antibody used in Western Blot (WB). GTX31094

Cat. No. GTX31094

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μl ($499)
See all Parkin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
Not tested in other applications.

Calculated MW

52 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM HEPES, 150mM NaCl, 0.01% BSA, 50% Glycerol

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser101 conjugated to KLH

Purification

Affinity Purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

parkin RBR E3 ubiquitin protein ligase , AR-JP , LPRS2 , PARK2 , PDJ

Cellular Localization

Cytoplasm, cytosol , Nucleus , Endoplasmic reticulum , Mitochondrion

Background

The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Parkin (phospho Ser101) antibody used in Western Blot (WB). GTX31094

GTX31094 WB Image

Anti-Parkin (phospho Ser101) antibody used in Western Blot (WB). GTX31094

GTX31094 WB Image

Western Blot: Parkin (phospho-Ser101) Antibody [GTX31094] - HEK293 cells transfected with Parkin WT (Phospho) and Parkin S101 mutant (non-phospho) showing the phospho-specific immunolabeling of the ~ 52 k parkin protein. The immunolabeling is absent in the parkin S101 mutant.

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Package List Price ($)
$ 499